GCSE Biology

Disease and response
revision.

Pathogens, immunity, vaccination and the control systems that keep conditions constant.

Disease and response guides

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05

Vaccination

Explain how vaccines work for GCSE Biology: dead or inactive pathogen, antigens, antibodies, memory cells, a faster secondary response, and herd immunity protecting people who cannot be vaccinated.

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06

Antibiotics and painkillers

Separate antibiotics from painkillers for GCSE Biology: antibiotics kill bacteria or stop growth, they do nothing to viruses, painkillers ease symptoms, and resistance evolves by natural selection (MRSA).

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07

Drug trials

Sequence preclinical and clinical drug trials for GCSE Biology: cells and tissues, animals, healthy volunteers, patients, double-blind placebo tests, and why peer review and sample size matter.

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08

Nervous system and reflexes

Sequence a reflex arc for GCSE Biology: stimulus, receptor, sensory neurone, relay neurone, motor neurone, effector, synapse with neurotransmitter, and why the brain is not a required stop.

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09

Endocrine system

Map GCSE Biology hormones: glands, blood transport, target organs, pituitary as master gland, and how chemical control is slower but longer-lasting than a nerve impulse.

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10

Blood glucose and diabetes

Control blood glucose for GCSE Biology: pancreas, insulin, glycogen in liver and muscle, glucagon on Higher tier, and the Type 1 versus Type 2 diabetes treatments examiners split.

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11

The kidney

Explain kidney function for GCSE Biology: filtration in the glomerulus, selective reabsorption of glucose and water, ADH and urine concentration, and dialysis versus transplant as kidney-failure treatments.

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12

Thermoregulation

Control body temperature for GCSE Biology: thermoregulatory centre, sweating, vasodilation, vasoconstriction, shivering, hair erection, and why enzymes need a set point near 37 °C.

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13

Reaction time required practical

Plan the GCSE Biology reaction-time investigation: ruler-drop or computer test, caffeine or tiredness as the independent variable, reaction time as the dependent variable, controls, mean and evaluation.

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